Chemistry

bone

Rice, Baylor win defense grant to advance metastasis study

Rice University chemist Han Xiao and biologist Xiang Zhang at Baylor College of Medicine have won a $2.3 million Department of Defense grant to expand their efforts to halt bone cancer metastasis.

Carbon nanotubes woven into thread-like fibers and sewn into fabrics become a thermoelectric generator that can turn heat from the sun or other sources into energy in a project developed at Rice University. (Credit: Jeff Fitlow/Rice University)

Woven nanotube fibers turn heat into power

Carbon nanotubes woven into thread-like fibers and sewn into fabrics become a thermoelectric generator that can turn heat from the sun or other sources into energy.

Illustration to highlight the launch of the Center for Adapting Flaws into Features.

NSF grant kicks off Center for Adapting Flaws into Features

Rice University has won a Phase I National Science Foundation grant to establish the NSF Center for Adapting Flaws into Features to investigate nanoscale chemical phenomena and optimize the structures and electronic properties of materials.

Rice University researchers introduced noncanonical amino acid building blocks into proteins in living cells, pioneering a powerful tool for investigating and manipulating the structure and function of proteins. The resulting unnatural organism, a strain of Escherichia coli bacteria, is able to monitor low levels of oxidative stress. (Credit: Xiao Lab/Rice University)

Programmed bacteria have something extra

Rice chemists expand genetic code of E. coli to produce 21st amino acid, giving it new abilities.

A novel antibody-drug conjugate targets cancer cells, but also kills "bystander" cancer cells. Credit: Illustration by the Jenna Kripal/Nicolaou Research Group

Targeted tumors attack not-innocent bystanders

Antibody-drug conjugates developed are found to attack not only targeted tumor cells but also nontargeted “bystanders.”

Scientists at Rice University and Baylor College of Medicine are using pClick conjugation to create therapeutic antibodies that target bone cancers. The conjugate incorporates bisphosphonate molecules that bind to the bone hydroxyapatite matrix. (Credit: Baylor College of Medicine/Rice University)

Drug doubles down on bone cancer, metastasis

Researchers at Rice University and Baylor College of Medicine develop an antibody conjugate called BonTarg that delivers drugs to bone tumors and inhibits metastasis.

Julian West

NIH grant will help streamline chemical synthesis

Rice University chemist Julian West has won a five-year, $1.8 million National Institutes of Health grant to advance his lab’s efforts to simplify the synthesis of organic chemicals.

Rice University synthetic chemists have simplified the process to make halichondrin B, top, the parent compound of the successful cancer drug eribulin, bottom. Their reverse synthesis reduced the number of steps required to make the natural product. (Credit: Jenna Kripal/Nicolaou Research Group)

Reversal speeds creation of important molecule

A Rice lab’s reverse approach to making halichondrin B is the shortest route to a “rather complex and important molecule."

The mechanism by Rice University chemists for the phase evolution of fluorinated flash nanocarbons shows stages with longer and larger energy input. Carbon and fluorine atoms first form a diamond lattice, then graphene and finally polyhedral concentric carbon. (Credit: Illustration by Weiyin Chen/Rice University)

‘Flashed’ nanodiamonds are just a phase

The “flash” process developed at Rice University can turn carbon black into functionalized nanodiamond and other materials. The carbon atoms evolved through several phases depending on the length of the flash.

Gang Bao

Sickle cell advance incorporates Rice lab's tech

Rice University bioengineer Gang Bao, a pioneer in the search for a way to treat and perhaps cure sickle cell disease, is co-author of a significant step forward revealed in Science Translational Medicine and led by his colleagues at Stanford University.

Three gas-phase molecules react at high temperatures during chemical vapor deposition to form molybdenum disulfide, a two-dimensional semiconductor that could find use in next-generation electronics. In this illustration, molybdenum atoms are purple, oxygen is red and sulfur is yellow. (Credit: Illustration by Jincheng Lei/Rice University)

Rice lab peers inside 2D crystal synthesis

Scientific studies describing the most basic processes often have the greatest impact in the long run. A new work by Rice University engineers could be one such, and it’s a gas, gas, gas for nanomaterials.

Sallyport

People, papers and presentations - May 28, 2021

People, papers and presentations - May 28, 2021

Biologists at Baylor College of Medicine, the Netherlands Cancer Institute and Rice University show in a study published in Science that the nuclear arrangement in a human cell can be turned into that typical of a fly. (Credit: Illustration by Evgeny Gromov)

Biologists construct a ‘periodic table’ for cell nuclei

A team of biologists studying the tree of life has unveiled a new classification system for cell nuclei, and discovered a method for transmuting one type of cell nucleus into another.

Rice owl burned in laser

In graphene process, resistance is useful

Lab uses laser-induced graphene process to create micron-scale patterns in photoresist for consumer electronics and more.

A preliminary rendering shows a concept for the lobby of the new science and engineering building on the site of the Abercrombie Engineering Laboratory, which will be demolished soon. (Credit: SOM)

Rice names architect for new engineering and science building

With the imminent demolition of Rice University’s Abercrombie Engineering Laboratory, the space will soon be cleared for a new engineering and science building, according to Rice administrators. International architecture firm Skidmore, Owings & Merrill (SOM) has been selected as lead architect for the new building. Houston’s Scientia Architects will consult on laboratory design.