CPRIT

Targeted tumors attack not-innocent bystanders

Antibody-drug conjugates developed are found to attack not only targeted tumor cells but also nontargeted “bystanders.”

Drug doubles down on bone cancer, metastasis

Researchers at Rice University and Baylor College of Medicine develop an antibody conjugate called BonTarg that delivers drugs to bone tumors and inhibits metastasis.

Cell-wrangling circuit simplifies genetic experiments

A Rice alumnus' work pays off with The Equalizer, a synthetic circuit that assures consistent gene expression in laboratory-bred colonies.

NIH grant will help streamline chemical synthesis

Rice University chemist Julian West has won a five-year, $1.8 million National Institutes of Health grant to advance his lab’s efforts to simplify the synthesis of organic chemicals.

Bioengineering department adds single-cell expert via CPRIT grant

The little things of life mean a great deal to Julea Vlassakis, who will bring her study of protein complexes and their role in cancer proliferation to Rice University this year.

Feds back probe of understudied gut nervous system

Rice University neurobiologist Rosa Uribe has won a five-year, $2 million R01 grant from the National Institutes of Health to study how the enteric nervous system develops.

B.J. Fregly named ASME Fellow

B.J. Fregly, a professor of mechanical engineering and bioengineering and a CPRIT Scholar in Cancer Research, has been named a fellow of the American Society of Mechanical Engineers (ASME).

Rice, Baylor part of research effort to advance genome editing

Researchers from Rice University and Baylor College of Medicine are part of a national effort to accelerate genome-editing research and develop gene-editing technologies and therapies.

Cancer ‘guardian’ breaks bad with one switch

A mutation that replaces a single amino acid in a potent tumor-suppressing protein makes it prone to nucleating amyloid fibrils implicated in many cancers as well as neurological diseases.

Cerium sidelines silver to make drug precursor

Rice scientists have developed a simplified method to make fluoroketones, a drug precursor that typically requires an expensive silver catalyst.

New CRISPR tech targets human genome’s complex code

Rice bioengineers harness the CRISPR/Cas9 system to program histones, the support proteins that wrap up and control human DNA, to manipulate gene activation and phosphorylation. The new technology enables innovative ways to find and manipulate genes and pathways responsible for diseases.

Rice chemist, alums named to Forbes 30 Under 30

Rice University chemist Julian West and four alumni have been named to the 10th annual Forbes 30 Under 30.

Vitamin boosts essential synthetic chemistry

Inspired by light-sensing bacteria that thrive near hot oceanic vents, synthetic chemists use vitamin B12 to catalyze valuable hydrocarbons known as olefins, or alkenes, useful precursor molecules for the manufacture of drugs and agrochemicals.

Once-discounted binding mechanism may be key to targeting viruses

Researchers detail subtle stabilizing effects in cells’ ability to recognize coronaviruses that compromise the immune system. The discovery could lead to new targets to prevent disease.

In a hurry to develop drugs? Here’s your cHAT

Rice University scientists develop cHAT to simplify the reduction of alkenes to more useful intermediate molecules for drugs and other useful chemical compounds.