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Kevin McHugh

Rice lands grant to improve time-release drugs

September 21, 2021

HOUSTON – (Sept. 21, 2021) – Time-released drugs are about to get a geometry lesson, thanks to bioengineers at Rice University.

B.J. Fregly

NIH funds effort to customize treatment of movement impairments

September 17, 2021

Existing treatments for movement impairments are “off the rack” rather than “custom-tailored,” but B.J. Fregly, a Rice University professor of mechanical engineering and bioengineering, wants to change that situation.

A study of stress on bacteriophage T7 will help Rice structural biologist Yang Gao and his team to reveal the atomic-scale mechanisms of DNA replication. Illustration courtesy of the Yang Gao Lab

Rice lab dives deep for DNA’s secrets

August 27, 2021

Structural biologist Yang Gao receives a five-year National Institutes of Health grant to detail how complex protein chains replicate DNA and fix errors on the fly. What they find could help treat genomic disease, including cancer.

Rice University has been awarded a $4 million grant by the Cancer Prevention and Research Institute of Texas to establish the Genetic Design and Engineering Center. (Credit: Illustration by Olivia Flynn/Bashor Lab)

CPRIT grant establishes Genetic Design and Engineering Center

August 20, 2021

Rice faculty members led by bioengineer Gang Bao have been awarded a $4 million CPRIT grant to establish the Genetic Design and Engineering Center.

Rice University researchers introduced noncanonical amino acid building blocks into proteins in living cells, pioneering a powerful tool for investigating and manipulating the structure and function of proteins. The resulting unnatural organism, a strain of Escherichia coli bacteria, is able to monitor low levels of oxidative stress. (Credit: Xiao Lab/Rice University)

Programmed bacteria have something extra

July 30, 2021

Rice chemists expand genetic code of E. coli to produce 21st amino acid, giving it new abilities.

A novel antibody-drug conjugate targets cancer cells, but also kills "bystander" cancer cells. Credit: Illustration by the Jenna Kripal/Nicolaou Research Group

Targeted tumors attack not-innocent bystanders

July 16, 2021

Antibody-drug conjugates developed are found to attack not only targeted tumor cells but also nontargeted “bystanders.”

Scientists at Rice University and Baylor College of Medicine are using pClick conjugation to create therapeutic antibodies that target bone cancers. The conjugate incorporates bisphosphonate molecules that bind to the bone hydroxyapatite matrix. (Credit: Baylor College of Medicine/Rice University)

Drug doubles down on bone cancer, metastasis

July 16, 2021

Researchers at Rice University and Baylor College of Medicine develop an antibody conjugate called BonTarg that delivers drugs to bone tumors and inhibits metastasis.

The Equalizer is a synthetic circuit that assures consistent gene expression from cell to cell in laboratory-bred colonies. (Credit: Illustration by Jin Yang)

Cell-wrangling circuit simplifies genetic experiments

July 6, 2021

A Rice alumnus' work pays off with The Equalizer, a synthetic circuit that assures consistent gene expression in laboratory-bred colonies.

Julian West

NIH grant will help streamline chemical synthesis

July 5, 2021

Rice University chemist Julian West has won a five-year, $1.8 million National Institutes of Health grant to advance his lab’s efforts to simplify the synthesis of organic chemicals.

Julea Vlassakis

Bioengineering department adds single-cell expert via CPRIT grant

June 26, 2021

The little things of life mean a great deal to Julea Vlassakis, who will bring her study of protein complexes and their role in cancer proliferation to Rice University this year.

CREST

Feds back probe of understudied gut nervous system

May 10, 2021

Rice University neurobiologist Rosa Uribe has won a five-year, $2 million R01 grant from the National Institutes of Health to study how the enteric nervous system develops.

B.J. Fregly

B.J. Fregly named ASME Fellow

April 21, 2021

B.J. Fregly, a professor of mechanical engineering and bioengineering and a CPRIT Scholar in Cancer Research, has been named a fellow of the American Society of Mechanical Engineers (ASME).

Gang Bao

Rice, Baylor part of research effort to advance genome editing

April 12, 2021

Researchers from Rice University and Baylor College of Medicine are part of a national effort to accelerate genome-editing research and develop gene-editing technologies and therapies.

Amyloid

Cancer ‘guardian’ breaks bad with one switch

March 5, 2021

A mutation that replaces a single amino acid in a potent tumor-suppressing protein makes it prone to nucleating amyloid fibrils implicated in many cancers as well as neurological diseases.

A mild process discovered by Rice University chemists could replace difficult, silver-based catalysis to create valuable fluoroketones, a precursor in the design and manufacture of drugs. Illustration by Renee Man/@chemkitty

Cerium sidelines silver to make drug precursor

February 26, 2021

Rice scientists have developed a simplified method to make fluoroketones, a drug precursor that typically requires an expensive silver catalyst.

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