CPRIT

Rice University bioscientists have uncovered a tiny detail that could help understand how DNA replicates with such astounding accuracy.

Crystal study may resolve DNA mystery

Rice University bioscientists have uncovered a tiny detail that could help understand how DNA replicates with such astounding accuracy.

Gang Bao

Rice trains postdocs for nano-cancer future

The National Institutes of Health extend a grant to help future medical professionals understand nanotechnology-enabled tools to treat cancer.

Caroline Ajo-Franklin

Living sensor research wins federal backing

Rice researchers are leading a federally funded project to improve communications between microelectronics and microorganisms.

Rice University bioengineer Omid Veiseh with a vial of bead-like implants his lab invented to serve as anti-cancer drug factories

‘Drug factory’ implants eliminate ovarian, colorectal cancer in mice

Rice bioengineers have created tiny implants that activate immune cells to destroy cancer.

A moderate amount of a peptide-enhanced cancer drug goes a long way in treating breast cancers that metastasize to the bone.

Antibody with engineered peptide targets bone metastasis

A moderate amount of a peptide-enhanced cancer drug goes a long way in treating breast cancers that metastasize to the bone.

Illustration

Awards boost biomed advances

Four faculty members and their collaborators win Advanced Research Projects Agency for Health seed grants.

Kevin McHugh

Rice lands grant to improve time-release drugs

HOUSTON – (Sept. 21, 2021) – Time-released drugs are about to get a geometry lesson, thanks to bioengineers at Rice University.

B.J. Fregly

NIH funds effort to customize treatment of movement impairments

Existing treatments for movement impairments are “off the rack” rather than “custom-tailored,” but B.J. Fregly, a Rice University professor of mechanical engineering and bioengineering, wants to change that situation.

A study of stress on bacteriophage T7 will help Rice structural biologist Yang Gao and his team to reveal the atomic-scale mechanisms of DNA replication. Illustration courtesy of the Yang Gao Lab

Rice lab dives deep for DNA’s secrets

Structural biologist Yang Gao receives a five-year National Institutes of Health grant to detail how complex protein chains replicate DNA and fix errors on the fly. What they find could help treat genomic disease, including cancer.

Rice University has been awarded a $4 million grant by the Cancer Prevention and Research Institute of Texas to establish the Genetic Design and Engineering Center. (Credit: Illustration by Olivia Flynn/Bashor Lab)

CPRIT grant establishes Genetic Design and Engineering Center

Rice faculty members led by bioengineer Gang Bao have been awarded a $4 million CPRIT grant to establish the Genetic Design and Engineering Center.

Rice University researchers introduced noncanonical amino acid building blocks into proteins in living cells, pioneering a powerful tool for investigating and manipulating the structure and function of proteins. The resulting unnatural organism, a strain of Escherichia coli bacteria, is able to monitor low levels of oxidative stress. (Credit: Xiao Lab/Rice University)

Programmed bacteria have something extra

Rice chemists expand genetic code of E. coli to produce 21st amino acid, giving it new abilities.

A novel antibody-drug conjugate targets cancer cells, but also kills "bystander" cancer cells. Credit: Illustration by the Jenna Kripal/Nicolaou Research Group

Targeted tumors attack not-innocent bystanders

Antibody-drug conjugates developed are found to attack not only targeted tumor cells but also nontargeted “bystanders.”

Scientists at Rice University and Baylor College of Medicine are using pClick conjugation to create therapeutic antibodies that target bone cancers. The conjugate incorporates bisphosphonate molecules that bind to the bone hydroxyapatite matrix. (Credit: Baylor College of Medicine/Rice University)

Drug doubles down on bone cancer, metastasis

Researchers at Rice University and Baylor College of Medicine develop an antibody conjugate called BonTarg that delivers drugs to bone tumors and inhibits metastasis.

The Equalizer is a synthetic circuit that assures consistent gene expression from cell to cell in laboratory-bred colonies. (Credit: Illustration by Jin Yang)

Cell-wrangling circuit simplifies genetic experiments

A Rice alumnus' work pays off with The Equalizer, a synthetic circuit that assures consistent gene expression in laboratory-bred colonies.

Julian West

NIH grant will help streamline chemical synthesis

Rice University chemist Julian West has won a five-year, $1.8 million National Institutes of Health grant to advance his lab’s efforts to simplify the synthesis of organic chemicals.