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Rice study unlocks breakthrough for breast cancer bone metastases

January 24, 2024

Rice University researchers in the lab of chemist Han Xiao have identified a promising new immunological pathway to treat stubborn bone tumors, one of most prevalent forms of metastases in breast cancer patients.

chemical hood

Fluorine catch-and-attach process could boost drug efficiency

November 13, 2023

Rice scientists have developed a new low-cost, safe and effective process to free up and reattach fluorine to chemical compounds. In pharmaceuticals, fluorine can expand lifetime, increase absorption and minimize side effects.

sickle cell disease

Rice expert available to comment on FDA decision on sickle cell disease therapy

October 31, 2023

Rice University’s Gang Bao is available to comment on today’s decision by the FDA on whether or not to approve a CRISPR-based therapy for sickle cell disease.

research illustration

DREAM tool for gene therapies uses ‘locally sourced’ components

October 9, 2023

Rice bioengineers developed a tool that activates silent or insufficiently expressed genes using human-derived building blocks and a CRISPR-based genome-targeting platform.

researchers

Two Rice bioengineers win NIH Director’s New Innovator awards

October 3, 2023

Rice bioengineers Jerzy Szablowski and Julea Vlassakis received the NIH Director’s New Innovator Award for their respective research projects. Szablowski’s work seeks to develop a noninvasive method of mapping gene expression, while Vlassakis is studying complex, single-cell level processes and interactions in pediatric bone cancer.

Gang Bao

NIH funds new Baylor/Rice genome editing testing center

September 27, 2023

A five-year, $3.9 million grant from the National Institutes of Health will help establish a joint Baylor College of Medicine/Rice University center to support the development and testing of new genome editing technologies.

CRISPR Cas13 system

Tiny CRISPR tool could help shred viruses

September 27, 2023

Rice scientists mapped out the three-dimensional structure of one of the smallest known CRISPR-Cas13 systems then used that knowledge to modify its structure and improve its accuracy.

Prototype THOR implant for 'closed-loop' cancer immunotherapy

Feds fund $45M Rice-led research that could slash US cancer deaths by 50%

September 26, 2023

The Advanced Research Projects Agency for Health has awarded a Rice-led team $45 million to rapidly develop an implant with sense-and-respond technology that could slash U.S. cancer-related deaths by more than 50%.

researchers

Protective particles allow engineered probiotics to report gut disease

August 16, 2023

Rice U. bioengineers developed a platform that enhances survival and function of probiotics engineered to diagnose inflammatory bowel disease in animals. The technology holds promise for minimally invasive disease monitoring and advanced smart therapeutics.

Carolyn Nichol

Education program tackles race-based cancer health disparities

August 10, 2023

Rice U.’s Carolyn Nichol has won a competitive 5-year, $1,038,544 NIH Science Education Partnership Award (SEPA) award to address race-based cancer health disparities by increasing underrepresented minority student populations’ engagement and participation in biosciences education.

research illustration

New software designs optimized, personalized treatments for movement impairments

July 27, 2023

A team of Rice University engineers has launched open-source software that constructs and uses personalized computer models of how individual patients move to optimize treatments for neurologic and orthopedic mobility impairments.

Gang Bao and team

NIH grant backs Rice lab’s sickle cell disease research

July 18, 2023

Rice University bioengineer Gang Bao and his team have won a grant from the National Institutes of Health to address critical questions surrounding the safety and efficacy of using gene editing to treat sickle cell disease.

Han Xiao

Rice chemist wins $3.2M National Cancer Institute grant

July 17, 2023

Rice University chemist Han Xiao has won a $3.2 million research project (R01) grant from the National Cancer Institute to develop the first tissue-specific epigenetic inhibitor drug to treat bone metastasis.

Xiang Zhang of Baylor College of Medicine and Han Xiao of Rice University

Rice, Baylor developing ‘glyco-immune’ checkpoint inhibitor

May 19, 2023

Researchers from Rice and Baylor College of Medicine are developing a first-of-its-kind “glyco-immune” checkpoint inhibitor for breast cancer survivors who develop metastatic bone cancer.

cell model

Experimental model gets cells to behave as they would in utero

May 8, 2023

Rice U.’s Aryeh Warmflash wins $1.9 million NIH grant to develop experimental cell models that can shed light on critical embryonic developmental processes.

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