Mike Williams

An electron microscope image shows intact Escherichia coli bacteria at top and E. coli leaking chromosomes (green) after disruption by an antimicrobial peptide at bottom. New models by Rice University scientists have determined peptides that invade bacteria and do their damage from the inside are underrated. Source: Wikipedia

For some peptides, killing bacteria an inside job

Rice scientists study the dynamics of the immune system’s antimicrobial peptides, which attack and eliminate harmful bacteria. They find peptides that invade bacteria and do their damage from the inside are underrated.

Using computational models and atomic force microscope experiments, researchers at the University of Houston and Rice University have identified a possible “Achilles’ heel” in the frustration of amyloid beta peptides as they dock to the fibrils that form plaques in patients with Alzheimer’s. The frustrated steps could open a window for drugs able to cap the fibril ends, preventing further aggregation. (Credit: Illustration by Yuechuan Xu/Peter Vekilov/University of Houston)

Docking peptides, slow to lock, open possible path to treat Alzheimer’s

Researchers have identified a possible “Achilles’ heel” in the frustration of amyloid beta peptides as they dock to the fibrils that form plaques in patients with Alzheimer’s disease.

An illustration shows how optical trapping could be used to investigate collective, force-generating properties in a complex of motor molecules. A National Science Foundation grant to Rice University to acquire an optical tweezer will advance researchers’ investigation of biological and inorganic molecules. (Credit: Diehl Lab/Rice University)

Tweezer grant pleases Rice researchers

Rice researchers have won an NSF grant to acquire a sophisticated optical tweezer microscope to manipulate, measure and monitor micron-scale particles.

The North Atlantic network of sites that preserve records of hurricanes stretches along the coast from Canada to Central America, but with significant gaps. A new study led by scientists at Rice University shows filling those gaps with data from the mid-Atlantic states will help improve the historical record of storms over the past several thousand years and could aid in predictions of future storms in a time of climate change. Illustration by Elizabeth Wallace

Nature’s archive reveals Atlantic tempests through time

Rice scientists uncover how natural archives can record Atlantic hurricane frequency over the past 1,000 years. SUMMARY: Rice University scientists uncover how natural archives can record Atlantic hurricane frequency over the past 1,000 years. More data is needed to help model how climate change will affect storms in the future.

Creative Ventures Fund

Rice announces new faculty funding opportunities

Rice's Office of Research launches three Creative Ventures Funds to seed faculty initiatives and guide them towards commercialization.

Matthew Tirrell

Welch Institute names Matthew Tirrell to chair Scientific Advisory Board

The Welch Institute for Advanced Materials has named Matthew Tirrell to chair its Scientific Advisory Board

Rice University theorists have calculated flexoelectric effects in double-walled carbon nanotubes. The electrical potential (P) of atoms on either side of a graphene sheet (top) are identical, but not when the sheet is curved into a nanotube. Double-walled nanotubes (bottom) show unique effects as band gaps in inner and outer tubes are staggered. (Credit: Yakobson Research Group/Rice University)

Double-walled nanotubes have electro-optical advantages

Rice theorists find that flexoelectric effects in double-walled carbon nanotubes could be highly useful for photovoltaic applications.

Simulations by scientists at the Rice University-based Center for Theoretical Biological Physics suggest how the SARS-CoV-2 spike infects cells. The illustration shows how the spike reconfigures itself in microseconds as it goes from pre- to post-fusion with target cells. The researchers suggest their work to reveal the mechanism by which the virus spreads could lead to new strategies to defeat COVID-19.

Sim shows how COVID virus infects cells

A simulation shows the complicated mechanism by which the SARS-CoV-2 virus may infect cells, leading to COVID-19.

An illustration depicts the atomic structure of double-layer borophene. In this image, all atoms are boron, with the pink atoms specifically involved in bonding between the layers. Courtesy of Northwestern University

Bilayer borophene is a first

Scientists make bilayer borophene for the first time. The versatile 2D material shows promise for quantum electronics, energy storage and sensors.

Person dialing phone number

Ethics survey shows a campus unafraid to speak up

A recent survey of Rice employees found that 99% of respondents were comfortable reporting ethical concerns to at least one resource on campus.

Man wearing smart shirt

‘Smart’ shirt keeps tabs on the heart

Carbon nanotube thread woven into athletic shirts gathered electrocardiogram and heart rate data that matched standard monitors and beat chest-strap monitors. The fibers are flexible and the shirts are machine washable.

A study of stress on bacteriophage T7 will help Rice structural biologist Yang Gao and his team to reveal the atomic-scale mechanisms of DNA replication. Illustration courtesy of the Yang Gao Lab

Rice lab dives deep for DNA’s secrets

Structural biologist Yang Gao receives a five-year National Institutes of Health grant to detail how complex protein chains replicate DNA and fix errors on the fly. What they find could help treat genomic disease, including cancer.

Rice University has been awarded a $4 million grant by the Cancer Prevention and Research Institute of Texas to establish the Genetic Design and Engineering Center. (Credit: Illustration by Olivia Flynn/Bashor Lab)

CPRIT grant establishes Genetic Design and Engineering Center

Rice faculty members led by bioengineer Gang Bao have been awarded a $4 million CPRIT grant to establish the Genetic Design and Engineering Center.

bone

Rice, Baylor win defense grant to advance metastasis study

Rice University chemist Han Xiao and biologist Xiang Zhang at Baylor College of Medicine have won a $2.3 million Department of Defense grant to expand their efforts to halt bone cancer metastasis.

Carbon nanotubes woven into thread-like fibers and sewn into fabrics become a thermoelectric generator that can turn heat from the sun or other sources into energy in a project developed at Rice University. (Credit: Jeff Fitlow/Rice University)

Woven nanotube fibers turn heat into power

Carbon nanotubes woven into thread-like fibers and sewn into fabrics become a thermoelectric generator that can turn heat from the sun or other sources into energy.