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Systems Synthetic and Physical Biology

 Rice University and its Biotech Launch Pad today announced a peer-reviewed publication in Nature Communications detailing the development of a novel and rechargeable device — an electrocatalytic on-site oxygenator (ecO2) that produces oxygen to keep cells alive inside an implantable “living pharmacy,” potentially improving the outcomes of cell-based therapies.

Rice Biotech Launch Pad announces rechargeable oxygenator in development to improve cell-based therapies

November 9, 2023

Rice University and its Biotech Launch Pad today announced a peer-reviewed publication in Nature Communications detailing the development of a novel and rechargeable device — an electrocatalytic on-site oxygenator (ecO2) that produces oxygen to keep cells alive inside an implantable “living pharmacy,” potentially improving the outcomes of cell-based therapies.

Rice theoretical physicist Evelyn Tang

Rice physicist Evelyn Tang is inaugural recipient of early career award

October 30, 2023

Rice theoretical physicist Evelyn Tang is an inaugural recipient of the Interdisciplinary Early Career Scientist Prize from the International Union of Pure and Applied Physics.

research illustration

DREAM tool for gene therapies uses ‘locally sourced’ components

October 9, 2023

Rice bioengineers developed a tool that activates silent or insufficiently expressed genes using human-derived building blocks and a CRISPR-based genome-targeting platform.

researchers

Two Rice bioengineers win NIH Director’s New Innovator awards

October 3, 2023

Rice bioengineers Jerzy Szablowski and Julea Vlassakis received the NIH Director’s New Innovator Award for their respective research projects. Szablowski’s work seeks to develop a noninvasive method of mapping gene expression, while Vlassakis is studying complex, single-cell level processes and interactions in pediatric bone cancer.

researchers

NSF backs Rice processor design, chip security research

September 27, 2023

Rice computer scientists have won two grants from the National Science Foundation to explore new information processing technologies and applications that combine co-designed hardware and software to allow for more effective and efficient data stream analysis using pattern matching.

Gang Bao

NIH funds new Baylor/Rice genome editing testing center

September 27, 2023

A five-year, $3.9 million grant from the National Institutes of Health will help establish a joint Baylor College of Medicine/Rice University center to support the development and testing of new genome editing technologies.

CRISPR Cas13 system

Tiny CRISPR tool could help shred viruses

September 27, 2023

Rice scientists mapped out the three-dimensional structure of one of the smallest known CRISPR-Cas13 systems then used that knowledge to modify its structure and improve its accuracy.

Prototype THOR implant for 'closed-loop' cancer immunotherapy

Feds fund $45M Rice-led research that could slash US cancer deaths by 50%

September 26, 2023

The Advanced Research Projects Agency for Health has awarded a Rice-led team $45 million to rapidly develop an implant with sense-and-respond technology that could slash U.S. cancer-related deaths by more than 50%.

lab photo

Split gene-editing tool offers greater precision

September 21, 2023

To make a gene-editing tool more precise and easier to control, Rice University engineers split it into two pieces that only come back together when a third molecule is added.

researchers

Protective particles allow engineered probiotics to report gut disease

August 16, 2023

Rice U. bioengineers developed a platform that enhances survival and function of probiotics engineered to diagnose inflammatory bowel disease in animals. The technology holds promise for minimally invasive disease monitoring and advanced smart therapeutics.

Han Xiao

Rice chemist wins $3.2M National Cancer Institute grant

July 17, 2023

Rice University chemist Han Xiao has won a $3.2 million research project (R01) grant from the National Cancer Institute to develop the first tissue-specific epigenetic inhibitor drug to treat bone metastasis.

Caleb Bashor

Reporters broadcast live, on-the-scene, inside living cells

July 10, 2023

Synthetic biologists from Rice University and Princeton University have demonstrated “live reporter” technology that can reveal the workings of signaling networks in living cells with far greater precision than current methods. The first-of-its-kind reporting tool can show how quickly signaling networks respond and how responses vary from cell to cell in time and space.

James Chappell

James Chappell wins NSF CAREER Award

March 27, 2023

Rice bioscientist James Chappell has won a National Science Foundation CAREER Award to develop RNA programming methods that can improve human health and the environment.

Rice University engineers compare wastewater ‘snapshots’ to daylong composite samples and find snapshots lead to bias in testing for the presence of antibiotic-resistant genes.

Daylong wastewater samples yield surprises

December 19, 2022

Rice engineers find snapshots lead to bias in testing wastewater for antibiotic-resistant genes.

Rice University synthetic biology graduate student Maxwell Hunt holds a plate of glowing E. coli

Pathogenic sensor’s surprising capabilities revealed

December 12, 2022

Rice synthetic biologists have uncovered new capabilities of a genetically encoded sensor that allows salmonella, E. coli and other pathogens to sicken millions of people each year.

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