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Systems Synthetic and Physical Biology

researchers

Protective particles allow engineered probiotics to report gut disease

August 16, 2023

Rice U. bioengineers developed a platform that enhances survival and function of probiotics engineered to diagnose inflammatory bowel disease in animals. The technology holds promise for minimally invasive disease monitoring and advanced smart therapeutics.

Han Xiao

Rice chemist wins $3.2M National Cancer Institute grant

July 17, 2023

Rice University chemist Han Xiao has won a $3.2 million research project (R01) grant from the National Cancer Institute to develop the first tissue-specific epigenetic inhibitor drug to treat bone metastasis.

Caleb Bashor

Reporters broadcast live, on-the-scene, inside living cells

July 10, 2023

Synthetic biologists from Rice University and Princeton University have demonstrated “live reporter” technology that can reveal the workings of signaling networks in living cells with far greater precision than current methods. The first-of-its-kind reporting tool can show how quickly signaling networks respond and how responses vary from cell to cell in time and space.

James Chappell

James Chappell wins NSF CAREER Award

March 27, 2023

Rice bioscientist James Chappell has won a National Science Foundation CAREER Award to develop RNA programming methods that can improve human health and the environment.

Rice University engineers compare wastewater ‘snapshots’ to daylong composite samples and find snapshots lead to bias in testing for the presence of antibiotic-resistant genes.

Daylong wastewater samples yield surprises

December 19, 2022

Rice engineers find snapshots lead to bias in testing wastewater for antibiotic-resistant genes.

Rice University synthetic biology graduate student Maxwell Hunt holds a plate of glowing E. coli

Pathogenic sensor’s surprising capabilities revealed

December 12, 2022

Rice synthetic biologists have uncovered new capabilities of a genetically encoded sensor that allows salmonella, E. coli and other pathogens to sicken millions of people each year.

Rice University scientists and engineers develop programmable bacteria that sense contaminants and release an electronic signal in real time.

Bacterial sensors send a jolt of electricity when triggered

November 2, 2022

Rice researchers develop programmable bacteria that sense contaminants and release an electronic signal in real time.

Rafael Verduzco

NSF backs bid to speed environmental tests for viruses

October 11, 2022

The NSF backs Rice University efforts to speed the analysis of wastewater for coronaviruses from hours to seconds.

Engineered living materials

Rice lab grows macroscale, modular materials from bacteria

September 22, 2022

Rice bioscientists have created bacteria that self-assembles into a material like putty that could soak up pollutants.

Rice University receives National Science Foundation support to turn living cells, starting with bacteria, into random-access memory devices. These will be able to store and report data about their environments.

Rice team eyes cells for sophisticated data storage

August 18, 2022

Rice University receives National Science Foundation support to turn living cells, starting with bacteria, into random-access memory devices. These will be able to store and report data about their environments.

NSF Fellowship winners Take the Cake

NSF awards 38 Graduate Research Fellowships to Rice students

April 22, 2022

The National Science Foundation has awarded 38 Graduate Research Fellowships to Rice University students.

Caroline Ajo-Franklin

Living sensor research wins federal backing

April 4, 2022

Rice researchers are leading a federally funded project to improve communications between microelectronics and microorganisms.

Lilie lab students

Inaugural class of Rice Innovation Fellows announced

February 17, 2022

The Provost’s Office and the Liu Idea Lab for Innovation & Entrepreneurship (Lilie) have announced the inaugural class of Rice Innovation Fellows, a program that will provide educational and financial support to the next generation of scientist- and engineer-led spinout ventures.

Matthew Bennett

Grant backs effort to build useful bacterial colonies

September 20, 2021

Rice scientists have won a grant to advance the development of custom-designed microbial colonies for a variety of applications.

worms

Light flips genetic switch in bacteria inside transparent worms

December 22, 2020

Researchers from Rice University and Baylor College of Medicine have shown that colored light can both activate and deactivate genes of gut bacteria in the intestines of worms. The research shows how optogenetic technology can be used to investigate the health impacts of gut bacteria.

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