Images produced by Rice University scientists illustrate changes in ectodermal fate composition as a result of controlling the duration of endogenous Wnt secretion and signaling. Inhibition of Wnt prior to, or at the time of, BMP4 treatment instruct colonies (left column) to form radial patterns of neural (cyan), surface ectoderm (magenta) and placodal (red) fates, while permitting secondary Wnt secretion instructs colonies (right column) to form a ring of neural crest (yellow) at the expense of placodal fates. (Credit: Warmflash Lab/Rice University)

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