The CaMKII protein at top docks in three pockets on twisted actin filaments in neurons, a process that researchers at Rice University, the University of Houston and The University of Texas Health Science Center at Houston (UTHealth) believe is important to forming long-term memory. The regulatory domain (red) on CaMKII also binds to incoming calmodulin proteins, which unzip the entire structure from actin and allow bundled filaments to reorganize. (Credit: Wolynes Research Lab/Rice University)

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