An illustration by Rice University statisticians based on a temporal lobe epilepsy dataset shows clear presurgical differences in the brains of patients in Cluster 1, who are more likely to be seizure-free one year after anterior temporal lobe resection, and those in Cluster 2, who are less likely to be seizure-free. The brighter blue regions of interest indicate greater interictal (the period between seizures) metabolic activity measured during PET scans. The regions are: (a) ipsilateral inferior parietal lobule, (b) contralateral inferior parietal lobule, (c) ipsilateral parieto-temporal cortex, (d) ipsilateral associative visual cortex, (e) contralateral associative visual cortex, (f) cerebellar vermis, (g) ipsilateral cerebellar hemisphere and (h) contralateral cerebellar hemisphere. (Credit: Vannucci Lab/Rice University)